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R21/Matrix-M Vaccine

Matrix-M Vaccine IAS Toppers

Vaccines manufacturer Serum Institute of India (SII) has started exports of ‘R21/Matrix-M’ malaria vaccine to Africa.

R21/Matrix-M Vaccine
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About R21/Matrix-M Vaccine:

  • Developed by the University of Oxford and the Serum Institute of India (SII), the R21/Matrix-M vaccine leverages Novavax’s adjuvant technology to enhance the immune response.
  • It targets P. falciparum, the most lethal malaria parasite predominantly found on the African continent.
  • It has been recognized as the second malaria vaccine endorsed by the World Health Organization (WHO) in 2023, following the RTS,S/AS01 vaccine.
  • R21/Matrix-M is the first malaria vaccine to achieve the WHO’s efficacy target of 75%.
  • Approval for its use has been granted in Burkina Faso, Ghana, and Nigeria.
  • The vaccine’s development received support from multiple organizations, including the European and Developing Countries Clinical Trials Partnership (EDCTP), the Wellcome Trust, and the European Investment Bank (EIB).

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